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Infertility Dictionary

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Anovulation
The total absence of ovulation
Antibodies
Chemicals made by the body to fight or attack foreign substances entering the body. Normally they prevent infection; however, when they attack the sperm or foetus, they can cause infertility.
Anticardiolipin Antibodies (ACA)
An antibody directed against cardiolipin. These are one of the antiphospholipid groups of antibodies. Approximately 80% of patients who have an antiphospholipid antibody problem will test positive for anticardiolipin antibodies, but the remaining 20% will test positive for one of the other six antiphospholipid antibodies.
Antiphospholipid Antibodies (APA)
The acquired autoantibodies to negatively charged phospholipids found in approximately 15% of patients diagnosed with recurrent pregnancy loss. A positive test indicates that a woman’s blood clots too fast, cutting off support to the foetus. The correlation between the presence of APA and in vitro fertilization success has been a point of controversy over the past several years. In 1999 Joe Massey, MD (RBA), in cooperation with several leading infertility centers in the US and Canada conducted a meta-analysis of studies examining the relationship between the presence of serum antiphospholipid antibodies to IVF success and found no significant association.
Antisperm Antibodies
Antibodies made by either the man or the woman that can attach to sperm and inhibit movement of sperm or fertilization. Antibodies are frequently positive in men who have had vasectomies and vasectomy reversals, or testicular injuries.
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