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INFERTILITY
SOME IMPORTANT FACTS & TIPS TO TREATMENT
DR.MOHAMEDASHRAF (Director, CRAFT)

Reasons for Female Infertility | Reasons for Male Infertility | Modern Treatments for male infertility| Modern Treatments for female infertility | IVF | ICSI | Risks | What you should know before infertility treatment


According to the latest statistics, the rate of infertility is on the rise. It is a phenomenon that is not confined to just Kerala or India. It is a global phenomenon, and the alarming factor is that it is on the rise everyday.

Infertility is not something that can be blamed on the male or the female. It can happen to either of the partners, (40%) or in some cases, it can happen to both. One cannot restrict it to either of the sexes.

The important thing however, is to have an awareness of it. This booklet is designed specifically with this in mind. It gives a broad outline of the causes of infertility, and also looks into the different treatments available.

FEMALE REPRODUCTIVE SYSTEM


HOW DOES CONCEPTION TAKE PLACE ?
Normally a healthy woman's' menstrual cycle lasts a period of 28-30 days. Ovulation (that is when an ovum is released from the ovary ) occurs within 10-15 days in the cycle.(day 1 is the first day of the mens.bleed) The released ovum is picked up by the fimbria. a finger-like part located at the end of the Fallopian tube and it is .placed in the ampullary portion of the tube(2nd part of the tube)and stays there for about 12 to 24 hours , waiting for the sperms. When the husband ejaculates the semen in the vagina , within minutes actively motile sperms find their way to the cervix(mouth of the uterus).The sperms are then stored safely for about 24 to 48 hours in the crypts of the cervical canal. From there the sperms periodically move towards the fallopian tube through the uterine cavity to meet with egg. Thus the male and the female gamates fuse together to form zygote.(fertilized egg).This zygote then takes about 4 to 5 days to reach back into the uterine cavity and then implants near the fundus of the uterus and then grows as embryo and then to foetus and further it completes it's growth over a period of 260 days to become a mature baby, which is then delivered through the vagina. Goto top of the page

WHY DOES CONCEPTION NOT TAKE PLACE ?
Unfortunately, this process doesn't happen in the case of everyone. The reasons are many, and 80% of the time they are specific. The other 20%, is classified as unexplained infertility happens due to any of the many reasons. Most of these are female related, and can be diagnosed only by very sophisticated medical examination.

Infertility in males is much easier to detect. The male genital organs are well exposed unlike the female organs which needs scanning & It can be ascertained by simple tests like to check sperms for motility, morphology and survival. Tests can also be conducted to check the final number of sperms that reach uterus after copulation (P.C.T) These are reasons good enough to indicate that infertility tests should always be conducted on the male partner first.

REASONS FOR FEMALE INFERTILITY

  • When ovulation (monthly ovum production) does not occur at all. (25 % - 30% of causes for infertility)
  • The fallopian tube can have a full or partial block (10 % -15% of causes for infertility) *
  • The cervical canal can have an infection, in which case sperms are killed at the very entrance of the canal.
  • Peritoneal factor: This is an illness called Endometriosis - a condition where tissues inside the uterus invades and damages the neighbouring reproductive organs like tube, ovary, and peritoneium this accounts for 40% of female infertility.(40 % of causes for infertility)
  • Fibroids and adenomyosis these are benign tumours developing in the body of the uterus.(5 % -10% of causes for infertility)
  • Pelvic adhesions mainly following previous surgery, may impaire tubo ovarian relations.


REASONS FOR MALE INFERTILITY

  • Disorder in the production of sperm
  • Inadequate number of sperms
  • Poor motility
  • Variations in shapes of sperm (presence of large number of abnormal shaped sperms)
  • Infection in prostrate gland or a block in the urinary tract
  • Infection or blocks in testis & epididymis
  • Presence of abnormal veins over the testicles known as varicocele
  • Inability of the man to ejaculate into the vagina

There are other reasons for male infertility too. Some of them are excessive smoking, excessive intake of intoxicants, mumps, injury to testis, urinary disorders, pain during ejaculation, use of tight underwear's, bathing in very hot water, sexually transmitted diseases, and stress related professions.Goto top of the page

VARICOCELE
It is seen in about 5% of general population and in about 25% infertile males.

Blood vessel that carry impure blood from testis may get blocked resulting in impure blood accumulation This causes increase in testicular temperature and consequently sperm production decreases. This is called varicocele. By a very simple micro surgery this can be corrected and it improves the semen profile provided varicocele is of significant grade (grade 2). Varicocele detected by the help of a scan and which is not evident clinically doesn't require any surgery.


MODERN TREATMENTS FOR MALE INFERTILITY

MICROSURGERY
With the advent of ART procedures micro surgical correction of male tubal block has become absolute.

Only in cases of hormonal deficiency, hormone replacement therapy is going to be effective and this is seen only in 5% of the males. Apart from this there is no other indication for hormone therapy. If the semen contains any bacteria this can be corrected by appropriate antibiotics.

SPERM WASHING AND CAPACITATION (IUI)
When there is no varicocele or hormonal deficiency the couple has a high chance of getting pregnancy after IUI where in a sample of semen is prepared in the laboratory by washing in culture medium and separating fast moving sperms by special techniques, is then deposited high in the uterus by a fine catheter around the time of ovulation is known as IUI . The success rate of IUI varies from 5 to 15% per cycle. After a maximum of five or six attempts there is no point in repeating the procedure .In this case a couple has to go for IVF or ICSI. Goto top of the page

STEP BY STEP IN IUI

  1. Drug treatment, to encourage two or three eggs to mature. Usually clomiphene and or gonadotropins are given to stimulate the growth of follicles and cause ovulation.
  2. Monitoring of treatment, to measure the growth of follicles, individualize drug doses and prevent serious side effects,By transvaginal ultrasound scanning (three or four times during a treatment cycle) Sometimes by measuring hormones in a blood sample.
  3. Sperm sample, provided on the morning of ovulation, is prepared and inserted later that day
  4. Pregnancy testing and monitoring after 15 days.

MICROMANIPULATION (ICSI)

This is yet another sophisticated method .In this method the selected sperm is made to enter the ovum with the help of a special microscope and manipulator. This is the most modern method in infertility treatments today. The techniques of intracytoplasmic sperm injection ,or ICSI have been hailed as a revolution in the past few years and have finally offered a viable treatment for even the most difficult cases of male infertility. Where in the past doctors could offer nothing but adoption or Dl (donor insemination) to those couples whose infertility was a result of severe sperm defects, now ICSI appears to offer a real treatment solution.

DIAGNOSIS OF FEMALE CAUSES
A wellconducted clinical exam and a transvaginal scan will give a lot of information as to the condition of genital organs.

If they are in perfect order the first test to do is to check for ovulation by serial scan, plus couple of hormones.

Next in order is to check the tubal patency, this is done in 3 ways;

If the pelvic anatomy is normal we can do either HSG (by X- ray) or by SSG (by scan).

If there is any disease in the pelvis these may not be rewarding so we have to do a laparoscopy.

The great advantage of it is at the same sitting we can correct the problems as well.

The next in order is to check for the sperm survival known as P.C.T. Goto top of the page

COMMON DISEASES LEADING TO FEMALE INFERTILITY AND THEIR MANAGEMENT

Endometriosis is a puzzling disease affecting girls and women in their reproductive years. The name comes from the word "endometrium", which is the tissue that lines the inside of the uterus and builds up and shreds each month in the menstrual cycle. In endometriosis, tissue like the endometrium is found outside the uterus, in other areas of the body. In these locations outside the uterus, the endometrial tissue develops into what are called "nodules", "tumors", "lesions", "implants", or "growths". These growths can cause pain, infertility, and other problems.

The most common locations of endometrial growths are in the abdomen - involving the ovaries, fallopian tubes, the ligaments supporting the uterus, the area between the vagina and the rectum, the outer surface of the uterus, and the lining of the pelvic cavity. Sometimes the growths are also found in abdominal surgery scars, on the intestines or in the rectum, on the bladder, vagina, cervix, and vulva (external genitals). Endometrial growths have also been found outside the abdomen, in the lung, arm, thigh, and other locations, but these are uncommon.

Symptoms

The most common symptoms of endometriosis are pain before and during periods (usually worse than "normal" men-strual cramps), pain during or after sexual activity, infertility, and heavy bleeding. Other symptoms may include fatigue; painful bowel movements with periods; lower back pain with periods; diarrhea and /or constipation and other intestinal upset with periods. Infertility affects about 30-40% of women with endometriosis and is a common result with progression of the disease.

The amount of pain is not necessarily related to the extent or size of growths. Tiny growths (called "petechial") have been found to be more active in producing prostaglandins, which may explain the significant symptoms that often seem to occur with small implants. Prostaglandins are substances produced throughout the body, involved in numerous functions, and thought to cause many of the symptoms of endometriosis. Goto top of the page

DIAGNOSIS
Diagnosis of endometriosis is generally considered uncertain until proven by laparoscopy.

TREATMENT
Treatment for endometriosis has varied over the years but no sure cure has yet been found.

About 40 % of the female infertility cases are attributed to Endometriosis. The most effective treatment in such a case is operative laparoscopy, in which endometrial growth is destroyed through laser treatment. This procedure can be conducted through an endoscopy, which does not require the abdomen to be opened.

In a span of just 6 years, the centre has conducted 4000 such surgeries. Of these, 63 % of them have been certified successful - with the patients going on to full-term pregnancies and subsequent deliveries.

The success of this procedure won the faculty the coveted "International Young Scientist Award" at the Endometriosis conference organised at Yokohama, Japan, in November 1996.

ANOVULATION
This is a disorder in the hormone production that facilitates ovulation .Among them the commonest variety is known as polycystic ovarian syndrome (PCOS).

Effective medicines are available to cure this problem, but the most effective treatment to PCOD is Endoscopic surgery (also known as Endoscopic Ovarian Drilling).

Around one in five women have polycystic ovaries. This term describes the appearance of the ovaries when they are seen on an ultrasound scan the polycystic ovary syndrome (PCOS) is the name given to a condition in which women with polycystic ovaries have polycystic ovary syndrome, but all women with PCOS do have polycystic ovaries.

The diagnosis of PCOS has been made much easier in recent years by the availability of ultrasound scanning .before this, only women with the most severe symptoms could be diagnosed with accuracy today ,the condition can be detected even when the problems are only mild.

SYMPTOMS OF PCOS
1. MENSTRUAL IRREGULARITIES
The imbalance of hormone production from both the ovaries and pituitary may result in either irregular ovulation or no ovulation at all (known as 'anovulation'). Menstrual periods may therefore become irregular -perhaps heavier than usual,perhaps occurring after long gaps (oligomenorrhoea) or perhaps not at all (amenorrhoea). Some women notice pelvic pain .which may be related to the effect of hormones on the flow of blood through the pelvic veins. Goto top of the page

2. FERTILITY
Irregular ovulation usually means that pregnancy is more difficult to achieve. Similarly ,if ovulation is not taking place ,it is just not possible to conceive without treatment. So women with irregular cycles hoping to get pregnant will have a better chance once their monthly cycles have returned to normal.

3. MISCARRIAGE
While miscarriage seems an unfortunate chance event for most couples, it is now known that women with PCOS who have high circulating levels of LH may be at greater risk. The explanation is probably that too high a level of LH in the blood stream makes it more difficult for the egg to develop within the follicle, and for an embryo to implant within the uterus.

4. SKIN PROBLEMS
One of the hormones which may be released from in unusually high amounts from the ovary is testosterone ,the male sex hormone which circulates in both men and women. Excessive 'testosterone levels in women may be a cause of acne on the face and back, or unwanted hair on the face .chest arms and legs. The levels of testosterone in women with PCOS are still much lower than those found in men.

The every day problems of PCOS are often only amenable to medical treatment, but there are also some lifestyle changes which can improve symptoms. For example doctors know that the body's hormone balance can be upset by the excessive body weight, and certainly PCOS is more common in obese women than in those with a correct weight to height ratio.
Equally some women with polycystic ovaries only develop symptoms when they put on weight .so a correct weight to height ratio will help, and this can be measured by an equation called 'the body mass index' (BMI). Your BMI is your weight in kilograms divided by your height in metres and then squared -or as doctors would write kilogram /metre square. A normal BMI is between 20 and 25. Goto top of the page

MANAGEMENT OF PCOS
It thus goes without saying that all women with polycystic ovaries should try to maintain a normal weight and to have regular periods. Medical treatment is usually confined to those with the troublesome symptoms of PCOS.

DRUGS TO INDUCE OVULATION
In case where ovulation is irregular or non-existant, drugs can be used. The most common is clomiphene citrate, which is taken as a tablet for five days from the second day of menstruation. Results show that four out of five women given clomiphene do ovulate ,but only about one in three actually become pregnant. The starting dose is usually 50 milligrams, which may be increased to 100 milligrams. Clomiphene can cause thickening of mucus in the cervix, so a post -coital test can tell doctors how well the sperms are surviving in a genital tract.

However, while clomiphene is a useful drug for many women with infertility problems, it is not always suitable for those with PCOS because it can cause an exaggerated rise in blood levels of LH which could impede fertilization or increase the chance of 10 miscarriage .so if clomiphene has not been successful in women with PCOS within six months, more investigations and alternative treatments are usually called for.

Side effects with clomiphene have been reported, notably stomach and bowel upsets, hot flushes, bloating, headache, dizziness, depression and breast discomfort. Multiple pregnancy is a risk whenever ovulation is induced with fertility dugs-in natural conception the risk is about one in eighty, in induced ovulation about one in twenty. There is no increased risk of birth defects from fertility drugs.

LAPAROSCOPIC OVARIAN DIATHERMY

A new, minimally -invasive operation which is performed through a laparoscope looks set to replace the more traumatic 'wedge resection' in which a part of the ovary was removed surgically. The new procedure -known as laparoscopic ovarian diathermy-actually burns parts of the ovary to correct any hormonal abnormalities and thus make ovulation possible. Goto top of the page

IN VITRO FERTILIZATION

IVF, The test tube baby technique in which a woman's egg are fertilized with the partner's sperm in the laboratory, is usually recommended to women who have blocked fallopian tubes, or men with poor sperm. IVF is sometimes offered to women with PCOS who want to conceive when other treatments have failed. However PCOS on it's own is not an indication for IVF. Women with PCOS who do undertake IVF are greater risk of the ovarian hyperstimulation syndrome and must be carefully monitored.

TUBAL BLOCK (BLOCK IN FALLOPIAN TUBE)
Almost 10 % of reported female infertility is due to a common problem called tubal block.

If the tubal block is at the tip of the fallopian tube, it can be removed either through endoscopic surgery or microsurgery . If the block is at the beginning, either utero tubal implantation after laparotomy or it could be tackled by tubal cannulation through hysteroscopy. Nowadays Tubal cannulation through endoscopyis widely recognized as the ideal solution. A special X-ray technique hystero salpingo graphy( HSG ) or diagnostic laparoscopy can be used to detect this. Another method of detecting tubal block is by sono salpingography which is done with the help of scan.

CERVICAL FACTOR
As mentioned earlier, the solution for this is to deposit a prepared sperm directly into the uterus or the fallopian tube. The medical terminology for this is known as Intra Uterine Insemination ( IUI ) . Other treatments available are IVF-ET, Micromanipulation, In Vitro Fertilization(IVF), (TET) Intra Cytoplasmic sperm Injection (ICSI)

INVITRO FERTILIZATION
IVF is the original test tube baby technique and probably the most widely practiced assisted-conception procedure in the world. In simple terms IVF removes several eggs from the ovary fertilizes them in the laboratory with sperm from the male partner, and transfers a small selection of the resulting embryos to the womb for implantation and pregnancy. Although IVF was developed to treat couples whose principal cause of infertility is tubal damage, the technique has also been found useful in those with endometriosis, sperm disorders (poor sperm counts or morphology) and even unexplained infertility. Studies indicate that the expectation of pregnancy from one cycle of treatment is around 25 percent, and the chance of delivery slightly less. Overall the average take-home baby rate from IVF is about 15 percent for each cycle of treatment. These rates are not much different from those of normal fertile couples. Most studies have shown pregnancy rates falling in women after the age of 35, which is why many infertility specialists encourage couples to act quickly when the female partner is already in early 30's. Goto top of the page

ICSI
The ICSI technique makes use of the most powerful microscopes and 'micromanipulators': embryologists ,for example .holding a single human egg at the end of a fine suction pipette, can penetrate the egg with a needle which is seven or more times finer than the diameter of the human hair. In normal, conception a single ejaculation of semen might contain more than 200 million viable sperms-but from this vast number only a few hundred will actually reach the released egg in the fallopian tube and be able to fertilize it. Men with total sperm counts below 20 million or so (or 5 million per millimeter) were always thought impossible to treat; now ICSI can achieve fertilization with just one sperm cell injected into an egg.

In males with no sperms known as azoospermia some times we can aspirate 5 or 10 mature sperms from the testes and these sperms can be utilized for ICSI thus these unfortunate males can also become fathers.

STEP BY STEP IN ICSI

  1. Drug treatment, to stimulate several eggs to mature
    - GnRH antagonist to suppress all other hormone activity (injections /nasal spray for (usually) two weeks before gonodotropins and then a further 10-14 days depending on response)
    - gonodotropins to stimulate the growth of follicles and cause ovulation
  2. Monitoring of treatment to measure the growth of follicles, individualize drug doses and prevent serious side effects.
    - Bytransvaginal ultrasound scanning (two or three times during a treatment cycle)
    -Sometimes by measuring hormones in a blood sample.
  3. Egg collection, usually under local anaesthetic, lasts between 10 and 20 minutes.
    - Guided by transvaginal ultrasound
    - Collected through the vagina (32-36 hours after final hormone injection)
  4. Sperm sample provided on same day as egg collection
    The sample can be obtained in natural way or following aspiration from the epididymis (MESA) or extraction from the testis (TESE)
  5. FERTILIZATION
    One single sperm cell is injected into a single egg cell Eggs are examined the next day under the microscope to see whether fertilization has occurred.
  6. EMBRYO TRANSFER (USUALLY TWO OR THREE DAYS AFTER FERTILIZATION)
    - Transvaginal transfer of no more than three embryos
    -embryos placed in the womb
    - Spare embryos usually frozen.
  7. PREGNANCY TESTING / MONITORING Goto top of the page


THE RISKS OF ASSISTED CONCEPTION

Because all assisted conception methods offer an overall chance of a baby of around 15 to 20 % for each cycle of treatment, the biggest hazard for those embarking on treatment is disappointment. However as studies show the chances of pregnancy do increase with additional cycles and are comparable to nature.

These are few risks associated with the actual treatments themselves. GIFT requires general anaesthesia for laproscopy to take place, and this can - on very rare occasions - cause complications. Indeed, this is one reason why infertility specialists in some countries have preferred IVF to GIFT - not because the results are better but because a general anaesthetic is not required.

The most common side effects of treatment are multiple pregnancies. These not only cause serious social complications (particularly as the babies begin to grow) but are also associated with higher rates of pregnancy loss and lower birth weight babies. The most published 'danger' of assisted conception had been a condition called 'ovarian hyperstimulation syndrome' (OHSS) which can very rarely occur as a result of the drug treatment given in the stages before the egg collection. Too high a dose of drug can cause excessive stimulation of the ovaries, which may be noticed as a pain in the abdomen. It is to avoid the risk -as well as the risk of multiple pregnancies - that doctors monitor drug treatment and it's effect on the ovary.

BLASTOCYST CULTURE
This is yet another effective method of infertility treatment. It improves the success rate of IVF and ICSI by 50%.

In the Blastocyst Culture, the 4 or 8 celled embryo is not transferred to the uterus. Instead it is allowed to divide again after which it becomes a multi celled complex entity called a Morule. In the next stage of division it is called a Blastocyst.

It is at this stage it is transferred to the uterus. The advantage here is that the Blastocyst sticks more lastingly to the uterus, thus reducing chances of rejection. The only disadvantage here is the difficulty involved to grow the embryo to the Blastocyst stage. Also we must get lot of embryos to grow 1 or 2 blastocysts.

ASSISTED HATCHING
Assisted Hatching is advantageous to those who have a history of failed IVF or ICSI.

If the female partner is above the age of 35, the ovum is likely tohave a thick outer layer (thick zone). Inevitably the covering layer of the embryo will also be thick. In such circumstances a hole is made on the outer layer of the ovum using the precision glass needle of a micromanipulator, after which the embryo will be able to break open the outer layer.

This treatment can be conducted using a laser beam or even acid tyroid.Goto top of the page

GENETIC STUDY
Almost 15% of infertility cases can be attributed to chromosome disorders. Studies have shown infertility to be caused by the loss of the y chromosome. In fact, it is the same anomalous sex chromosome that causes premature ovarian failure (the state of being incapable to produce ovum) among females. Anomaly of xx or xy chromosome is said to be the reason for 5 % of neonatal death and still born cases.

PRENATAL DIAGNOSES
Modern medical science now offers facilities to find out the variation of chromosomes. This is called prenatal diagnosis.

When a woman becomes pregnant after the age of 35, the likelihood of having a baby affected with Down's Syndrome increases. This is because there is an excess number of 21st chromosomes are formed in the foetus.

If the first born child is mentally or bodily handicapped the second too is likely to become that way. Especially when either the male or female partner suffers from chromosome disorders. By conducting the pre-natal test we can get to know if the child in the womb has any malformation.

This knowledge, along with the advice of a good medical counsellor will help you to arrive at a right decision.

4D SCAN
The VOLUSON730 scanner helps to sort out complex structures quickly.

It offer much benefit in the evaluation of suspected fetal anomalies, growth reduction etc.

"Having the voluson 730 in our office drives satisfaction not only with our staff but also with the patients we care for patients appreciate being able to visualize their babies moving three dimensions. With other systems, 3D reconstructions were tedious and time consuming. The voluson 730 gives us the highest quality 3D and real time 4Dinstantly. The voluson 730 allows me to see and evaluate fetal movement unlike any other ultrasound system on the market. Beyond this outstanding 3D the volusion 730 delivers competitive high-end 2Dimage resolution"

WHAT YOU SHOULD KNOW BEFORE AN INFERTILITY TREATMENT
Prior to an infertility treatment, it is essential one should know the following facts:

  1. If you suspect infertility, consult a reliable doctor immediately.
  2. Infertility can be suspected only if regular sexual intercourse without contraceptives does not yield any result at least after one year. In cases where the woman is above 30 years of age , a check for infertility is advised if there is no pregnancy reported within six months of unprotected intercourse.
  3. Infertility is not the fault of the woman alone. Either husband or wife may be infertile. In such cases tests should be run to find out for which of the partners the problem is.
  4. For the treatment process, take care in choosing the doctor and the hospital. A good hospital with modern facilities would be the ideal choice.
  5. Before the treatment get a correct assessment of the costing.
  6. Ask your doctor about the success rate of every treatment. Just in case the treatment you choose has only a 10 % chance of success, you could assess the financial situation and decide whether to go in for the treatment or not. If the treatment get more complicated ask the doctor the likely success rate of it. Sometimes you will have to spend for treatment which does not even ensure 10% success.
  7. If the treatment within your financial status does not yield positive results there is always the option of legal adoption. But then again, if there is a hesitancy to adopting, the couple can even think about a life without children or babies.
    The myth that children will look after their parents during old age is not quite true.Goto top of the page

ESSENTIAL INFORMATION FOR THOSE WHO REGISTERED HERE FOR INFERTILITY TREATMENT

FOR SCANNING
It has to be done in the morning of the 10th day of the menstrual cycle, and has to be continued everyday for the next five days. Along with scanning Post Coital Test ( PCT) can also be done. To do this test, the couple should have had intercourse 12 hours prior to it. Those who do not need a PCT but are doing Follicular Scanning should make sure they have sexual intercourse from the 10th day of the menstrual cycle to the 15th day.

  • Before scanning, make sure the bladder is empty.
  • If, during the treatment, at any point of time period starts again, the doctor has to be informed immediately.
  • If pregnancy is confirmed, the doctor has to be informed.

FOR ENDOSCOPIC SURGERY
Those patients who come for endoscopic surgery should get admitted one days prior to it. Under normal circumstances, the patient is discharged after 24 hours. 2-3 days rest at home is necessary, after which normal life can ensue.

  1. For those who are travelling a long distance for the IUI treatment, it is advisable to come prepared for a 2-3 days stay in the hospital.
  2. The endoscopic surgery is recordable. Those who want to record the surgery should entrust a cassette with the duty nurse prior to the surgery.


THE INFERTILITY CLINIC

  1. The clinic, CRAFT .attached to K J Hospital is one of the most reputed infertility clinics in Kerala.
  2. It offers all modern medical facilities and has helped turn many infertility cases into success stories
  3. The speciality of surgery at CRAFT is that the patient has to spend only 1 or 2 days in the hospital, after which a few days of bed rest are sufficient to bring back normalcy.
  4. Endoscopic Surgery done here is so specialised, it can be made use of for a wide range of uterus related illnesses -excessive bleeding, fibroids and ovarian cysts can all be corrected through the same procedure.
  5. To rectify urinary tract disorder, CRAFT performs the Burch Colpo Suspension Surgery. This is also done by Endoscopy.
  6. Endoscopy can also be used to set right the fallopian tube, after sterilization
  7. BALOON THERAPY In cases of severe bleeding from the uterus where conception is not a problem this is an ideal way to stop the bleeding with out removing the uterus. Goto top of the page


ALMOST ALL THESE FACILITIES ARE ALSO AVAILABLE IN DUBAI CLINIC AS WELL


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